Acute adverse reactions to psychoactive drugs, drug usage, and psychopathology.

A field survey method was used to examine the relationship between psychopathology and acute adverse reactions to psychoactive drugs. A paper-andpencil measure of acute adverse reactions was discussed. Acute adverse reactions were hypothesized to covary positively with regression, schizophrenia, and drug usage, and to covary negatively with adjustment and paranoia. These hypotheses were supported. Usage of LSD and mescaline was hypothesized to covary positively with regression and covary negatively with adjustment; these hypotheses were supported. A hypothesis that schizophrenia would positively covary with LSD and mescaline usage was not confirmed. Regression was also found to be related to marijuana usage. A recursive linear model is developed in an attempt to integrate and explain these results.